Eva Istvan, PhD

Associate Professor of Medicine

Dr. Istvan specializes in the biochemistry of Plasmodium falciparum, the most deadly malaria parasites of humans. She is an active member of research laboratory lead by Dr. Daniel E. Goldberg. Dr. Istvan is particularly focused on the identification of new anti-malarial targets and mechanisms of resistance. In Dr. Goldberg’s laboratory, she performs research, manages research equipment and protocols and assists students and post-docs with their experiments.

Related Links
  • BS, summa cum laude, Biochemistry and Chemistry: University of Houston, Houston, TX (1993)
  • Phd, Molecular Biophysics: Laboratory of Dr. J. Deisenhofer, University of Texas Southwest Medical Center (2000)
  • Postdoctoral Fellow: Laboratory of Dr. J. Deisenhofer, University of Texas Southwest Medical Cemter (2001)
  • Postdoctoral Fellow: Laboratory of Dr. D. E. Goldberg, Washington University School of Medicine (2006)
  • Nominata Award, highest award of UTSW graduate school, 05/2000
  • Molecular Parasitology Speaker Award, 09/2003 and 09/2008
  • Molecular Parasitology Poster Award, 09/2014
Selected Publications
  1. va S. Istvan, Sudipta Das, Suyash Bhatnagar, Josh R. Beck, Edward Owen, Manuel Llinás, Suresh M. Ganesan, Jacquin C. Niles, Elizabeth A. Winzeler, Akhil B. Vaidya, Daniel E. Goldberg (2019). Plasmodium falciparum Niemann-Pick Type C1-Related Protein is a Druggable Target Required for Parasite Membrane Homeostasis. Elife. 2019 Mar 19;8:e40529. doi: 10.7554/eLife.40529.PMID: 30888318
  2. Eva S. Istvan, Jeremy P. Mallari, Victoria C. Corey, Neekesh V. Dharia, Garland R. Marshall, Elizabeth A. Winzeler, Daniel E. Goldberg (2017). Esterase mutation is a mechanism of resistance to antimalarial compounds. Nat Commun. 2017 Jan 20;8:14240. doi: 10.1038/ncomms14240.PMID: 28106035

Bibliography – Eva Istvan