Investigator Labs

philips-tb-inf-macrophage-red-blue-green1290

TB infected macrophage – contributed by Jennifer A. Philips, MD, PhD, Associate Professor of Medicine

 

  • Megan T. Baldridge Lab: The Baldridge Lab studies the interactions of the intestinal commensal microbiota with viral and bacterial pathogens.
  • Jacco Boon Lab: The Boon Lab is interested in understanding the mechanisms and determinants involved in pathogenesis of the influenza virus.
  • Michael S. Diamond Lab: The Diamond Lab focuses on the interface between viral pathogenesis and the host immune response in mosquito-borne human pathogens such as Zika, West Nile and Dengue virus.
  • James Fleckenstein Lab: The Fleckenstein Lab focuses on the molecular pathogenesis of enterotoxigenic Escherichia coli (ETEC), a major cause of mortality in young children due to diarrheal illness in developing countries.
  • Daniel E. Goldberg Lab: The Goldberg Lab uses biochemical, genetic, genomic, cell biological and physiological approaches to study the malaria parasite.
  • Jeffrey P. Henderson Lab: The Henderson Lab uses interdisciplinary approaches to better understand infections caused by Gram negative bacteria and to identify new therapeutic strategies.
  • Robyn Klein Lab: The Klein Lab focuses on the pathogenesis of neuroinflammatory diseases of the central nervous system (CNS).
  • Jennie H. Kwon Lab: The Kwon lab is devoted to exploring novel and practical techniques to improve methods to detect, prevent, and treat antimicrobial resistance in the human and environmental microbiome
  • F. Matthew Kuhlmann, MD, MSCI Lab – We focus on understanding the interaction between malnourished hosts and their response to enteropathogens.
  • George B. Kyei Lab: The Kyei Lab is focused on characterizing the HIV reservoir and HIV replication, as well as identifying the molecular factors required for HIV reactivation in latently infected
  • Daisy W. Leung Lab: The Leung Lab is focused on understanding mechanisms regulating interactions between non-segmented, negative strand RNA viruses and host proteins that can be targeted therapeutically.
  • Mark J. Miller Lab: The Miller Lab uses advanced imaging approaches to study the cellular mechanisms of immunity during infection and inflammation.
  • Jonathan J. Miner Lab:  Rare rheumatic diseases, vasculitis, innate immunity, and viral pathogenesis
  • Makedonka Mitreva Lab: The Mitreva Lab focuses on the development of new and existing computational tools to enable structural and functional characterization of microbial systems and communities.
  • Jennifer A. Philips Lab: The Philips Lab is studying the molecular mechanisms of tuberculosis to better understand host immunity and bacterial pathogenesis.
  • Liang Shan, PhD Lab: His current research focuses on immune response to HIV-1infection. He uses humanized mouse models to develop vaccination strategies to target HIV-1 latent reservoir.
  • Jonathan Sheehan Lab: Personalized Structural Biology to help biomedical
    researchers approach their question from a molecular viewpoint. I can contribute a mechanistic hypothesis, structural analysis, or the interpretation of experimental results in the context of a protein’s structure-function relationship.
  • Haina Shin Lab: The Shin Lab is examining immune responses against viruses that establish persistent infections in their hosts.
  • Gary J. Weil Lab: The Weil Lab is devoted to research on filarial nematode parasites that cause important diseases in animals and humans (lymphatic filariasis and onchocerciasis), mainly in the tropics