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Hilary E.L. Reno, MD, PhD

Associate Professor of Medicine



Additional Titles

  • Medical Director, St. Louis County Sexual Health Clinic
  • Medical Consultant, CDC, Division of STD Prevention
  • Medical Director, St. Louis STD/ HIV Prevention Training Center
  • Director, St. Louis STI Regional Response Coalition

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  • BS: Nothern Illinois University, DeKalb, IL (1994)
  • MS: Entomology, University of Illinois-Urbana, Champaign, IL (1998)
  • PhD: Entomology, University of Illinois-Urbana, Champaign, IL (2000)
  • Medical Degree: University of Illinois-Urbana, Champaign, IL (2002)
  • Residency, Internal Medicine: Barnes-Jewish Hospital, St. Louis, MO (2005)
  • Chief Resident: Washington University School of Medicine, St. Louis, MO (2007)
  • Fellowship, Infectious Diseases: Barnes-Jewish Hospital, St. Louis, MO (2009)

Board Certifications

  • Internal Medicine
  • Infectious Disease

Clinical Interests

I am the medical director of the St. Louis County Health Clinic as well as an HIV and transgender health provider.

Ongoing projects work to improve clinical operations in the Emergency Department and Sexual Health clinics through near point of care testing, implementation and linkage to PrEP, and novel testing and treatment models including express visits and outreach testing.

As a medical consultant with the CDC, Division of STD Prevention (2016-2020), I focus in the area of STD clinical operations as well as the development of STI care toolkits and STI treatment guidelines.

Research Interests

My primary research interests are to improve the quality of care for patients with sexually transmitted diseases.  Using large databases of patients seeking care for STIs, we hope to develop a cooperative, regional approach to identify disparities in health care and reduce STI rates. Our research questions strive to improve care for priority populations such as sexual and gender minority persons, pregnant women, and racial minority persons. I also collaborate with researchers in microbiome work, especially focused on bacterial vaginosis.



C. Cohen, M. Wierzbicki, A. French, S. Morris. S. Newmann, H. Reno, L. Green, S. Miller, J. Powell, T. Parks, A. Hemmerling. Randomized Trial of LACTIN-V to Prevent Recurrence of Bacterial Vaginosis. N Engl J Med. 2020 May 14;382(20):1906-1915. doi: 10.1056/NEJMoa1915254.

H. Reno, B Fox, C Highfill, A McKee, A Trolard, S Liang, BP Stoner, B Meyerson. The emerging intersection between injection drug use and early syphilis in non-urban areas of Missouri, 2012-2018.  2020.  J Infect Dis. 2020 Sep 2;222(Supplement_5):S465-S470. doi: 10.1093/infdis/jiaa056.

Bergquist EP, Trolard A, Fox B, Sebert Kuhlmann A, Loux T, Liang SY, Stoner BP, Reno H. Presenting to the Emergency Department Versus Clinic-Based Sexually Transmitted Disease Care Locations for Testing for Chlamydia and Gonorrhea: A Spatial Exploration. Sex Transm Dis. 2019 Jul;46(7):474-479. doi: 10.1097/OLQ.0000000000001007. PMID:  31192889

Dretler AW, Trolard A, Bergquist EP, Cooper B, Liang SY, Stoner BP, Reno H. The influence of race and sex on gonorrhea and chlamydia treatment in the emergency department. Am J Emerg Med. 2019 May 30. pii: S0735-6757(19)30366-3. doi: 10.1016/j.ajem.2019.05.054. [Epub ahead of print]
PMID:  31182362