Maria Cristina Vazquez Guillamet, MD

Maria Cristina Vazquez Guillamet, MD

Associate Professor of Medicine

Dr. Guillamet’s focus has been bringing new mathematical and statistical methods to the study of infections in critically ill patients. She has been interested in infections caused by multidrug resistant microbes, their epidemiology, treatment and impact.

Her research aims at how to better predict and understand who’s at risk for developing an infection caused by multidrug resistant microbes. her current subjective approach has lead to both underrecognizing sepsis and also overtreating for MDR pathogens. More so, current prediction models have failed the external validation. Dr. Guillment strives to correct that and develop tools that classify patients at risk and that are easy to understand, apply and extrapolate.

Related Links
Office location

Northwest Tower
4990 Children’s Place
St. Louis, MO 63110

  • MD: University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania (2005)
  • MPH: University of Bucharest, Mater of Social and Healthcare Service. Bucharest, Romania (2007)
  • Residency – Internal Medicine – Yale New Haven Health Bridgeport Hospital, Bridgeport, CT (2010)
  • Fellowship – Critical Care Medicine – Stanford University, Stanford, CA (2012)
  • Fellowship – Infectious Diseases – Washington University in ST Louis, St Louis, MO (2013)
  • Fellowship – Infectious Diseases – University of New Mexico, Albuquerque, NM (2014)
Board Certifications
  • American Board of Internal Medicine
  • American Board of Internal Medicine, Subspecialty of Infectious Diseases
  • American Board of Internal Medicine, Critical Care Medicine
  • 2003-2004, 2004-2005 Merit scholarship for academic results
  • 2004: The 8th Medical Students and Young Doctors National Congress, Bucharest, Romania:  first prize in surgical section
  • 2004: The 8th Medical Students and Young Doctors National Congress, Bucharest, Romania:  Honorable mention in preclinical sciences section
  • 2008: winner of medical knowledge national contest at American Geriatrics Society Meeting
  • 2010: recipient of travel award ATS 2010, New Orleans, LA
  • 2010: recipient of “Pasquale Perillie” Award for Outstanding Leadership and Scholarship, Yale University, Bridgeport Hospital, CT
  • 2012: recipient of travel award ATS 2012, San Francisco, CA
  • 2013: recipient of trainee award IDSA 2013, San Francisco CA
Selected Publications
  1. Race Does Not Impact Sepsis Outcomes When Considering Socioeconomic Factors in Multilevel Modeling.Vazquez Guillamet MC, Dodda S, Liu L, Kollef MH, Micek ST.Crit Care Med. 2021 Jul 13. doi: 10.1097/CCM.0000000000005217. Online ahead of print. PMID: 34259658
  2. A  Pragmatic Machine Learning Model To Predict Carbapenem Resistance.McGuire RJ, Yu SC, Payne PRO, Lai AM, Vazquez-Guillamet MC, Kollef MH, Michelson AP. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0006321. doi: 10.1128/AAC.00063-21. Epub 2021 Jun 17. PMID: 33972243
  3. Interleukin-6 Trajectory and Secondary Infections in Mechanically Ventilated Patients With Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Treated With Interleukin-6 Receptor Blocker. Vazquez Guillamet MC, Kulkarni HS, Montes K, Samant M, Shaikh PA, Betthauser K, Mudd PA, Reynolds D, O’Halloran J, Lyons P, McEvoy C, Vazquez Guillamet R. Crit Care Explor. 2021 Feb 3;3(2):e0343. doi: 10.1097/CCE.0000000000000343. eCollection 2021 Feb. PMID: 33554125 Free PMC article.
  4. Next Steps in Pneumonia Severity Scores. Vazquez Guillamet MC, Kollef MH. Clin Infect Dis. 2021 Mar 15;72(6):950-952. doi: 10.1093/cid/ciaa184. PMID: 32123903
  5. Methicillin-resistant Staphylococcus aureus Nasal Screening Adds Limited Value to the Choice of Empiric Antibiotics in Community-acquired Pneumonia. Burnham JP, Kakol MK, Vazquez Guillamet MC. Clin Infect Dis. 2019 Mar 19;68(7):1251. doi: 10.1093/cid/ciy868. PMID: 30304410 Free PMC article. No abstract available.
  6. Predicting Resistance to Piperacillin-Tazobactam, Cefepime and Meropenem in Septic Patients With Bloodstream Infection Due to Gram-Negative Bacteria. Vazquez-Guillamet MC, Vazquez R, Micek ST, Kollef MH. Clin Infect Dis. 2017 Oct 30;65(10):1607-1614. doi: 10.1093/cid/cix612. PMID: 29020294
  7. Vazquez Guillamet C, Kollef MH. Acinetobacter Pneumonia: Improving Outcomes With Early Identification and Appropriate Therapy. Clin Infect Dis. 2018 Oct 15;67(9):1455-1462. Vazquez Guillamet MC, M Bernauer, S Micek, M Kollef. Cluster analysis to define distinct clinical phenotypes among patients with bloodstream infections. Medicine (Baltimore) 2019 Apr:98(16):e15276

Bibliography – Maria Cristina Vazquez Guillamet