2025 AGENDA INFECTIOUS DISEASES RESEARCH SYMPOSIUM

Agenda

June 17, 2025
1:00 – 5:00 pm
ID Annual Research Symposium
Eric P. Newman Education Center, 320 S. Euclid Ave., St. Louis, MO 63110

12:30 p.m.In person attendee check-in
1:00 p.m.EPNEC Seminar Room B
Welcome and Introductory Remarks
Jennifer A. Philips, MD, PhD
Theodore and Bertha Bryan Professor, Departments of Medicine and Molecular Microbiology; Co-director, Infectious Diseases Division

William G. Powderly, MD, J. William Campbell Professor of Medicine, & Co-director, Infectious Diseases Division
Larry J. Shapiro Director, Institute for Public Health
Associate Dean for Clinical and Translational Research
Director, Institute of Clinical and Translational Sciences
1:05 p.m.Pandemic Preparedness Through a Diagnostic Lens
Nira Pollock, MD, PhD, MMSc, D(ABMM)
Co-Director, Infectious Diseases Diagnostic Laboratory
Boston Children’s Hospital
Associate Professor of Pathology and Medicine
Harvard Medical School
Selected oral presentations Part 1
2:00 – 3:00 p.m.
2:00 p.m.
Kinetics of dissemination in the human fungal pathogen Cryptococcus neoformans
Zanetta Chang, MD, PhD, ID fellow

2:15 p.m.
Duration and Quantification of Histoplasma capsulatum Antigenuria During Treatment of Histoplasmosis in Patients by Immune Status

Sam Fallon, BA, medical student

2:30 p.m.

Inflammatory Markers and T Cells Associated with High-Risk Plaques in Persons with and without HIV
Syed Zaidi, MD, ID fellow

2:45 p.m.
Distinct gut microbiome features characterize Fasciola hepatica infection and predict triclabendazole treatment outcomes in Peruvian patients
Giljae Lee, postdoc research associate
3:00 p.m.Break (refreshments)
Selected oral presentations Part 2
3:15 p.m. – 4:00 p.m.
3:15 p.m.
Resident Macrophages Regulate Immune-Mediated Damage to the Enteric Nervous System During Viral Infection
Hana Janova, PhD, Staff Scientist

3:30 p.m.
Moderated Panel Discussion
Barbara Trautner, MD, PhD
Professor of Medicine and Co-Chief of the ID Division (July 1)

Jeffrey Henderson, MD, PhD
Professor of Medicine and Molecular Microbiology

Juliane Bubeck-Wardenburg, MD, PhD
Professor, Pediatric Critical Care
St. Louis Children’s Hospital

Margaret Olsen, PhD, MPH
Statistical Data Analyst III
ID Division


4:00 p.m.Refreshments and Poster Session
EPNEC Mezzanine – Poster Presentations 
(until 5:00 p.m.)

Posters by Category

Clinical
  1. Duration and Quantification of Histoplasma capsulatum Antigenuria During Treatment of Histoplasmosis in Patients by Immune Status
    Samuel Fallon, Julio C. Zuniga-Moya, M.D.; Andrej Spec, M.D., MSCI; Adriana M. Rauseo, M.D.
  2. Exploring Risk Factors for Attributable Mortality from Fusariosis in Hematological Cancer Patients
    David Schantz, Gayathri Krishnan, MD, MHPE ,Anupam Pande, MD, MPH, FIDSA
  3. Recent pregnancy is associated with decreased HCV treatment in people with opioid use disorder
    Caroline Cary, Kevin Xu MD MPH, Megan Curtis MD MS
  4. Safety and tolerability of SYN-004 in allogeneic hematopoietic cell transplant (HCT) recipients receiving meropenem (MER) or piperacillin/tazobactam (P/T)
    Erik Dubberke, Mark A. Schroeder, Kimberly A. Reske, Tiffany Hink
  5. A Metabolome-Derived Diagnostic for Clostridioides difficile Infection
    John Robinson, Hideji Fujiwara, Erik Dubberke, Jeffrey Henderson
Education

6. A Scoping Review of IDWeek Medical Education Abstracts
Amy Meyer, Darcy Wooten, Christian Hendrix, Josh Nordman, Miguel Chavez, Nathan Nolan, Nico Cabrera, Reid Goodman, Tri Pham, Gayathri Krishnan

Epidemiology & Prevention

7. Influence of environmental factors over the incidence of histoplasmosis:  A Pilot Study in 3 Midwestern States
Julio Zuniga-Moya, Benjamin Papadopoulos, Andrej Spec, Andrew Atkinson

8. The Complete Story: Packaged Testing and the Gaps in Sexually Transmitted Infection Screening
Tri Pham, Nick Cardoza, BS, Germysha Little, PhD , Andrew Atkinson, PhD, Benjamin Cooper, MPH, Hilary Reno, MD PhD

Global Health: global health work that does not fall under other basic science pathogenesis work

9. Genomics of carbapenemase producing carbapenem-resistant Enterobacterales carriage and acquisition in adult surgical intensive care unit patients in an Indian tertiary care hospital
Emily/Lindsey Benedict/Hall, Lindsey Hall, Emily Benedict, Sumanth Gandra

10. Community Readiness Assessment for Sustainable Youth-friendly HIV Prevention Services in Nigeria: A Qualitative Approach
Chiyere Arinze, Lateef Akeem Blessing, Juliet Iwelunmor, PhD, Oliver Ezechi, MBBS, PhD

11. New diagnostic tests to detect parasite proteins in the blood of people with heavy Loa loa infections
Philip Budge, Sarah Greene, Molecular Helminthology Lab

12. A pragmatic PLAN to sustain situationally tailored, innovative strategies to promote evidence-based health interventions in Nigeria: insights from a 5-week participatory co- creation and capacity building event.
Temitope Ojo, Folahanmi Akinsolu, Olufunto Olusanya, Juliet Iwelunmor

13. Cost-effective infrastructure and clinical capacity building in Cote d’Ivoire
Philip Budge, Lexi Dyer, Laura Peer

14. No-one-size-fits all: Using Mega-Innovation Bootcamp Events to Design and Finalize Implementation Strategies for Implementing Evidence-Based Interventions in Community Settings in Nigeria
Nkiruka Obodoechina, Ucheoma Nwaozuru PhD, Folahanmi Akinsolu PhD, Juliet Iwelunmor PhD

15. Intersectional Stigma and Resilience in the Uptake of Cervical Cancer Prevention Services: A Qualitative Study in Nigeria
Angel Obiorah, Agatha Wapmuk, Ifeoma Obionu, Juliet Iwelunmor

16. Designing for the Dissemination of Evidence-Based Youth-led HIV Self-Testing Intervention for Nigerian Youth: Findings from Crowdsourcing Open Call
Maria Afadapa, Ucheoma Nwaozuru PhD, Chisom Obiezu-Umeh PhD, Juliet Iwelunmor PhD

Implementation/Public Health

17. Correlates and pathways of antiretroviral treatment discontinuation: A comprehensive analysis of associated factors and self‐reported reasons for discontinuation.
Ellen Mukwekwerere, Aaloke Mody, Elvin H. Geng, Lindsey M. Filiatreau

18. HIV Assets for Retention and Mobilization to Benefit East Africa (HARAMBEE)
Eric Thuo, Harriet Adhiambo, Thomas A Odeny, Dickens Onyango, Betsy Abente, Joe Tucker, Elvin Geng

19. From Crisis to Connection: HIV Care Telehealth as an Antidote to Loneliness During the COVID-19 Stay-at-Home Era
Julia López, Shanti Parikh, Zeles Vargas, Khadijah Kareem

20. The Role of Music for Enhancing High Blood Pressure Control and Stroke Preparedness: Insights from an Innovation Bootcamp in Lagos, Nigeria
CHIDI OKAFOR, Shravya Allena, MPH,  Washington University In St. Louis -School of Medicine, Saint Louis, MO, United States, 2. Olaoluwaposi Ogunlana, College of Medicine, University of Ibadan, Ibadan, Nigeria, 3.  Olufunto A. Olusanya, PhD, MD, MPH,  Washington Univ

21. Organizational Readiness to Sustain HIV Prevention Interventions Among Adolescents and Young Adults in Nigeria
Chiyere Arinze, Olufunto Olusanya PhD, MBBS, MPH, Temitope Ojo PhD, MPH, Juliet Iwelunmor, PhD

22. Nothing for communities without communities: Expanding the reach of evidence- based interventions in Nigeria through crowdsourcing opening calls
Onyekachukwu Anikamadu, Folahanmi Akinsolu, PhD, Olufunto Olusanya, MD,MPH, PhD, Juliet Iwelunmor, PhD

23. Advancing Underrepresented Youth-Friendly Prevention Strategies Through Participatory COVID-19 Self-Testing Interventions: Findings from the I-TEST COVID-19 Study
Emily Miller, Juliet Iwelunmor, Temitope Ojo, Shravya Allena

24. Effects of the 4 youth by youth HIV prevention intervention on Sexually Transmitted Infections Uptake Among Adolescents and Young Adults in Nigeria: Findings from a Stepped-Wedge Cluster-Randomized Trial.
Peter Kalulu, Oluwakorede J. Adedeji, Arinze Chiyere, Juliet Iwelunmor

25. A designathon to collaboratively develop sustainable HIV prevention services for youth with community-based organizations: a mixed methods analysis of a crowdsourcing open call and designathon
Caven Ngoe, Titilola Gbajabiamila, Olufunto Olusanya, Juliet Iwelunmor

Pathogenesis

26. Investigating the Thermosensing Mechanism of the Capsule Regulator KvrA in Klebsiella pneumoniae
Emily Marino, Analea Scott, Dariana A. Chavez, and David. A. Rosen

27. Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2 in mice
Pritesh Desai, Courtney Karl, Chieh-Yu Liang, Baoling Ying, Larissa B. Thackray and Michael S. Diamond

28. Generation of novel anti-Bourbon Virus glycoprotein Monoclonal Antibodies
Houda Harastani, Ya-Nan Dai, Reed Trende, Jackson S. Turner

29. Identification of functional structural motifs in Influenza A virus
Astha Joshi, Lin Chen Huang, Adrianus C M Boon

30. ClpX and ClpXP Are Critical Determinants of Klebsiella pneumoniae Virulence and Antibiotic Susceptibility
Nathan Lin, David. A. Rosen

31. Single Cell Transcriptomics of HIV-Associated Kaposi Sarcoma in Kenya: a Pilot Study
Paula Valiño, Daniel Rauch, Lee Ratner, Thomas Odeny

32. Characterizing interactions between RSV and the actin cytoskeleton
Teresa Vitali, Daisy W. Leung

33. TRANSCRIPTIONAL REGULATION OF HOST IMMUNE RESPONSES BY HUMAN RESPIRATORY SYNCYTIAL VIRUS NON-STRUCTURAL PROTEIN 1
Parismita Kalita, Gaya K. Amarasinghe, Jacqueline E. Payton, Daisy W. Leung

34. A single-cell transcriptome atlas of adult male and female human hookworm Ancylostoma ceylanicum
SUMAN BHARTI, Bruce A Rosa, John Martin, Makedonka Mitreva

35. Macro meets T: Signaling Lymphocyte Activation Molecule Family Member 1 (SLAMF1) promotes protective immunity against Mtb through Macrophage-T cell interaction
G V R Krishna Prasad, SJ Grigsby, E Mittal, I Chen, G Erkenswick-Watsa, C Portal-Celhay,  N. Jain, A Martinot, JD Ernst, JA Philips

36. Distinct gut microbiome features characterize Fasciola hepatica infection and predict triclabendazole treatment outcomes in Peruvian patients
Giljae Lee, Bruce A. Rosa, Miguel M. Cabada, Makedonka Mitreva

37. Characterizing Microbial Dynamics within Skin Microbial Communities
Spring Goodson, Aayushi Uberoi

38. ETEC Heat-Labile Toxin Activates WNT/β-Catenin Signaling and Disrupts Intestinal Epithelial Homeostasis
Alaullah Sheikh, Bipul Setu, John Martin, Bruce Rosa, Makedonka Mitreva, and James Fleckenstein

39. Elucidating the Role of Conserved Secondary Motifs in Influenza A Virus Genome Packaging and Replication
Lin-Chen Huang, Astha Joshi, Adrianus C M Boon

40. Evolutionary Tuning of IRG1 Expression: Unraveling Species-specific Regulation of a Key Immunometabolic Gene
Ata Canbaz, Dustin Baldridge, Paul Hime, Anthony Orvedahl

41. Early transcriptional responses of mouse proximal colon and colonoids during whipworm infection
Hyeim Jung, Joseph F. Urban Jr., Bruce A. Rosa, Makedonka Mitreva

42. Inflammatory Markers and T Cells Associated with High-Risk Plaques in Persons with and without HIV
Syed Zaidi, Cullen Soares,  Marcela Araujo de Oliveira Santana , Shashwatee Bagchi

43. R5 tropic HIV restricts X4 tropic virus via type I IFN signaling, limiting pathogenesis
Priya Pal, Sara Nicholson, Bailey Quinn Hongbo Gao, Liang Shan

44. Mapping virulence-associated quorum sensing by the Yersiniabactin metallophore system of pathogenic Enterobacterales
Van Nguyen, Jeffrey Henderson

45. Kinetics of dissemination in the human fungal pathogen Cryptococcus neoformans
Zanetta Chang, Tamara L Doering

46. HPV and Vaginal Microbiome
Sonia Whang, Jiafen Hu, Nicole M. Gilbert

Stewardship

47. Routine admission urinalysis has low clinical utility in psychiatric hospitalizations
Tri Pham, Alice Bewley, MS; Sena Sayood, MD

48. Impact of an Antimicrobial Stewardship Rotation for Internal Medicine Residents
Marcela Araujo de Oliveira Santana, Noah Romero Nakajima, Darcy Wooten, Sena Sayood

49. Resident Macrophages Regulate Immune-Mediated Damage to the Enteric Nervous System During Viral Infection
Hana Janova, Hana Janova, Fang R. Zhao, Larissa Thackray, Thaddeus S. Stappenbeck, Michael S. Diamond

50. AMR-INFORMED ANTIBIOTIC USE METRICS
Reid Goodman, Alice Bewley, MS, Andrew Atkinson, PhD, M Cristina Vazquez Guillamet, MD

51. Impact of an Antimicrobial Susceptibility Reporting Change for Serratia marcescens
Kaytlin Bishop, PharmD; Christine Lockowitz, PharmD, BCIDP; Tamara Krekel, PharmD, BCPS, BCIDP; David Ritchie, PharmD, FCCP, BCIDP; Emily Welch, PharmD, BCPS; Taryn Mondiello, PharmD, BCACP, AE-C; David Rosen, MD, PhD; Rebekah Dumm, PhD, D(ABMM); Tristan Timbrook, PharmD, MPH, MBA, BCIDP, FIDSA; Elizabeth Neuner, PharmD, BCIDP