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William G. Powderly, MD

J. William Campbell Professor of Medicine & Co-director, Infectious Diseases Division



Additional Titles

  • Larry J. Shapiro Director, Institute of Public Health
  • Director, Institute of Clinical and Translational Sciences

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  • MB, BCh, BAO: University College, Dublin, Ireland (1979)
  • Residency: St. Vincent's Hospital, Dublin, Ireland and Mater Misericordiae Hospital, Dublin, Ireland (1983)
  • Fellowship, Infectious Diseases: Washington University School of Medicine, St. Louis, MO (1987)
  • Membership: Royal College of Physicians of Ireland (1981)


1992 Fellow, Royal College of Physicians of Ireland
1994 Fellow, Infectious Diseases Society of America, 1994
1999 FIRST AIDE award, 1999, St. Louis Effort for AIDS
2001 Twenty Heroes award, 2001; AIDS Foundation of St. Louis
2003 Fellow, American Association for the Advancement of Science
2016 Pillar of Support Award, Academic Women’s Network, Washington University
2017 President, Infectious Diseases Society of America
2018: Fellow, Royal College of Physicians (London)
2019 Distinguished Graduate Award by University College Dublin (UCD) Medical Graduates Association

Clinical Interests

Dr. Powderly heads the clinical activities (patient care and research) of the Infectious Diseases faculty and fellows.

Research Interests

Dr. Powderly has been actively involved in HIV-related clinical research for thirty years.  He has been a member of numerous advisory groups on HIV and infectious diseases for the National Institutes of Health (NIH), the U.S. Centers for Disease Control and Prevention, the Canadian Institute for Health Research, and the European Medicines Agency. He is currently a member of the NIH’s Office of AIDS Research Advisory Council. He also was the first chairman of the HIV Medicine Association.   He is the author of over 400 original manuscripts, reviews and book chapters.  His recent focus as Director of the Institute for Public Health has been on translating scientific advances to a wider population to improve public health.  The Institute under his direction has focused on Implementation Science, Community Partnerships, Economic and Policy Research, and Global Health to broaden the impact of discovery science and address disparities in health outcomes.

He is a Fellow of the Royal College of Physicians In Ireland, the Royal College of Physicians (London) and the American Association for the Advancement of Science, and was, in 2017, President of the Infectious Diseases Society of America.


Powderly WG. The Importance of Inclusion, Diversity, and Equity to the Future of the Infectious Diseases Society of America. J Infect Dis. 2019 Aug 20;220(Supplement_2):S82-S85. doi: 10.1093/infdis/jiz197. PMID:  31430378

Hevey MA, Presti RM, OʼHalloran JA, Larson L, Raval K, Powderly WG, Spec A. Mortality After Cryptococcal Infection in the Modern Antiretroviral Therapy Era.J Acquir Immune Defic Syndr. 2019 Sep 1;82(1):81-87. doi: 10.1097/QAI.0000000000002095. PMID: 31408451

Spec A, Pullman J, Thompson GR, Powderly WG, Tobin EH, Vazquez J, Wring SA, Angulo D, Helou S, Pappas PG; Mycoses Study Group. MSG-10: a Phase 2 study of oral ibrexafungerp (SCY-078) following initial echinocandin therapy in non-neutropenic patients with invasive candidiasis. J Antimicrob Chemother. 2019 Jul 15. pii: dkz277. doi: 10.1093/jac/dkz277. PMID: 31304536