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Anne Mobley Butler, PhD, MS

Instructor in Medicine


Office location

Northwest Tower
4990 Children's Place
St. Louis, MO 63110


  • BS - Neuroscience & Behavioral Biology: Emory University, Atlanta GA (2003)
  • MS - Epidemiology: Harvard School of Public Health (2006)
  • PhD - Epidemiology: Gillings School of Global Public Health, University of North Carolina at Chapel Hill (2014)
  • Postdoctoral Fellowship - Epidemiology: Gillings School of Global Public Health, University of North Carolina at Chapel Hill (2015-2017)

Research Interests

Dr. Butler’s research involves the application of epidemiologic study designs and analytic methods to highly detailed, clinical and administrative data that are captured on patients as part of routine clinical care. Her pharmacoepidemiology research focuses on the treatment and prevention of common infections, including antibiotic and vaccine utilization, effectiveness, safety, and related outcomes. Dr. Butler’s work utilizes data from various national databases including US commercial claims, Medicare, Medicaid, United States Renal Database System, Flatiron, and other clinical cohorts. Given that various patient populations are rarely included in clinical trials, results generated from these studies provide much needed evidence to inform decisions related to clinical practice, health policy, and quality improvement interventions. Dr. Butler has a secondary appointment in the Division of Public Health Sciences at Washington University School of Medicine.


Butler AM, Layton JB, Krueger WS, Kshirsagar AV, McGrath LJ. Assessing residual bias in estimating influenza vaccine effectiveness: comparison of high-dose versus standard dose vaccines. Medical Care. 2018 Nov 12. doi: 10.1097/MLR.0000000000001018. [Epub ahead of print]

McGrath LJ, Layton JB, Krueger WS, Kshirsagar AV, Butler AM. High-dose influenza vaccine use among patients receiving hemodialysis in the United States, 2010-2013. Vaccine. 2018 Oct 1;36(41):6087-6094. doi: 10.1016/j.vaccine.2018.08.079. Epub 2018 Sep 6.

Butler AM, Cetin K, Hernandez RK, Overman RA, Kim J, Reams BD, Hirsch BR, Abernethy AP, Liede A, Brookhart MA. Treatment dynamics of bone-targeting agents among men with bone metastases from prostate cancer in the United States. Pharmacoepidemiology and Drug Safety 2018 27(2):229-238.

 Butler AM, Layton JB, Li D, Hudgens MG, Boggess KA, McGrath LJ, Becker-Dreps S. Predictors of low uptake of prenatal tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis immunization in privately-insured women in the United States. Obstetrics and Gynecology 2017; 129(4):629-637.

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